See more In general, you can take over-the-counter (OTC) famotidine (Pepcid AC, Zantac 360) at any time of the day or night to help treat heartburn symptoms
If you are taking this medication once daily, it is usually taken right before It is usually taken once daily at bedtime or two to four times a day
Important considerations
Famotidine (Pepcid AC) is a histamine-2 (H2) antagonist that's used to treat conditions that cause too much stomach acid to build up, such as heartburn and stomach
Use the dosing syringe provided, or use a medicine dose-measuring device
To prevent heartburn and acid indigestion, take famotidine 15-60 minutes before eating food or drinking beverages that can cause indigestion
Famotidine decreases the amount of acid the stomach produces and is used to treat certain
PEPCID may be taken with or without food [see