Less than 3% of a doxepin dose is excreted in the urine as parent compound or nordoxepin
Clearance
loss of appetite
Doxepin is also used to treat people with
Adults and children 12 years of age and older—At first, 75 milligrams (mg)
Doxepin Hydrochloride Capsules USP
Doxepin may be used to treat symptoms associated with
Dry mouth
It is usually applied four times a day, at least 3 to 4 hours apart, for up to 8 days
loss of appetite
Doxepin tablets are not scored
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Talk with your doctor before using this medicine if you plan to have children
The orexin system regulates the sleep arousal cycle that promotes wakefulness
If you experience any other symptoms which you think may be due to the medicine, speak with your doctor or pharmacist for further advice
To reduce the Doxepin and its active N-demethylated metabolite are distributed into milk in concentrations ranging from about 30–140% and 10–115%, respectively, of those in maternal serum
Ease of Use
Doxepin commonly produces a 5:1 (E): (Z) racemic mixture
There are 27 disease interactions with doxepin which include: depression
acute myocardial infarction recovery
Itchy skin
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Chronic urticaria (off-label use): Oral: Adults: 10 mg 3 times daily (Greene 1985) or 10 mg to 30 mg once daily at bedtime (Yadav 2009)