Research paper about phenytoin

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    The title compounds were prepared according to the synthetic strategy described in Scheme 1

    The metabolism of Phenytoin to the major metabolite, 5-(p-hydroxyphenyl)-5-(phenylhydantoin, is saturable, giving rise to a non linear dose-serum concentration relationship, so the dose range compatible with a therapeutic serum concentration is narrow within subjects, and monitoring serum concentrations is of particular value in dosage

    Therapeutic drug monitoring of phenytoin was carried out to make sure effective and safe levels

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    442 Words; 2 Pages; Open Document

    1007/s13311-015-0372-8 A new series of phenytoin derivatives 4 a-j have been designed via one-pot three component reaction of aryl aldehyde derivatives 1 a-j with thiosemicarbazide (2) and benzil (3) in presence of sodium alkoxide

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    Several international pharmacopoeias specify liquid chromatography (LC) or titration with sodium hydroxide or sodium methoxide as the assay for purity of phenytoin, and LC, gas chromatography (GC) with flame ionization

    Although it has potential uses in nutraceutical research, it has developed into a A method for preparing phenytoin sodium was first reported by Biltz in 1908 (Budavari, 1995)

    Phenytoin

    The new oral high molecular weight hyaluronic acid gel can improve the impaired healing of diabetic wounds and could be useful in treating oral ulcerations

    Its powerful antioxidant, anti-inflammatory, and antitumour effects have great prospects in clinical application

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