Does tamoxifen cause uterine polyps

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  • January 2004 edited March 2014 #1
  • 5%) had endometrial polyps; however, 22 (51
  • Metindir et al
  • Cancer: Approximately 5 percent of endometrial polyps are malignant
  • Causes Hormonal factors appear to play a role
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  • fibroids
  • infertility in premenopausal people
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  • secondary breast cancer
  • Uterine polyps, also known as endometrial polyps, form as a result of cells in the lining of the uterus (endometrium) overgrowing

    Endometrial disease in the tamoxifen group included 2,882 cases of polyps, 1,911 cases of hyperplasia, 307 cases of cancer, and 71 other uterine cases

    Causes and Risk Factors Treatment to Remove Endometrial Polyp (s) Endometrial polyps are abnormal growths that form within the uterine lining

    Figure 2

    endometrial polyps: occurs in ~8-36% of women in treated 8 endometrial hyperplasia: occurs in ~1-20% of women treated ref cystic endometrial atrophy

    January 2004 edited March 2014 #1 I took tamox

    6% in the

    Examples of aromatase

    Endometrial polyps, the most common abnormality, were diagnosed in 33% of biopsies performed for endometrial thickness of 8 mm or more

    EPs often arise in the common womanly patients and are appraised to be about 25%

    43-fold increase in uterine hyperplasia

    Prevention of tamoxifen induced endometrial polyps using a levonorgestrel releasing intrauterine system long-term follow-up of a randomised control trial

    An endometrial polyp or uterine polyp is a mass in the inner lining of the uterus

    Endometrial polyps can be removed during hysteroscopy, a procedure that uses a tiny telescope (hysteroscope) and thin surgical instruments to view and treat areas inside the uterus

    One of the main concerns with tamoxifen

    They may show stromal fibrosis and periglandular stromal condensation

    Another contributing factor may be taking the breast cancer drug tamoxifen (18, 19)

    Department of Surgery, Tzanion General Hospital, Piraeus, Greece

    Other types of cancer can form in the uterus, including uterine sarcoma, but they are much less common than endometrial cancer

    The exact cause of endometrial polyps in women is not known

    Moreover,an increase in the hyperdiploid fraction in endometrial biopsies--a markerfor endometrial proliferation--has been associated with the Endometrial polyps are localized hyperplastic overgrowths of endometrial glands and stroma around a vascular core that form a sessile or pedunculated projection from the surface of the endometrium ( picture 1) [ 1,2 ]

    In a few cases, use of tamoxifen in postmenopausal women may cause polyps or ovarian cysts or, even more rarely, cancer of the womb

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  • Does tamoxifen cause uterine polyps
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