Apr 26, 2023 · Clinical importance of these pharmacokinetic effects unknown; however, topiramate can cause metabolic acidosis, a condition for which the use of metformin is contraindicated Oral contraceptives Substantial decrease in ethinyl estradiol exposure reported in patients receiving an oral contraceptive containing ethinyl estradiol and norethindrone Major See more Topiramate is approved by the U
The comparison between concomitant use of topiramate and metformin revealed that topiramate has a robust therapeutic effect on obesity induced by some SGAs during the vast majority of follow-up visit in this trial
All subjects The clinical significance of the effect of topiramate on metformin pharmacokinetics is not known
Although there are some existing data describing the usage of topiramate in patients with antipsychotic-induced obesity, study on its comparison with metformin is limited
It is used in diabetes
Studies show that on average, people taking Topamax lose around 11 lbs
Topiramate may cause vision problems that can be permanent if not treated quickly
Topiramate is also used to prevent migraine headaches but not to relieve the pain of migraine headaches when they occur in adults and children 12 years of age and older No differences were observed with respect to weight loss or insulin resistance indexes
Symptoms include nausea, vomiting, fast breathing, and lethargy
menstrual changes or pain
You shouldn’t use these medications together
drowsiness
Note: For oral dosage form (extended-release capsules): Adults and children 12 years of age and older—At first, one tablet of 3
For example, you might take a dose in the morning at 8 am and a dose at night at 8 pm
Weight loss
Both Topamax and metformin can With metformin I stopped getting dizzy spells, and started losing weight with no changes to my diet (started without the intent to lose weight)
Oral plasma clearance of topiramate appears to be reduced when administered with metformin
Taste disturbances, diarrhea, and other stomach-related side effects are common side more
Topiramate add-on treatment to prevent or reverse antipsychotic drug-induced weight gain has been studied in several trials as well
What’s interesting is that the percentage of weight loss achieved in each individual was independent of age, sex, or BMI
Topiramate alone can result in weight loss, as well, but oftentimes we do use the two in Using metFORMIN together with topiramate may increase the risk of a rare but serious and potentially life-threatening condition known as lactic acidosis, which is a buildup of lactic acid in the blood that can occasionally occur during treatment with metformin-containing products
The most common symptoms are vomiting, diarrhea, and nausea, which affect anywhere from 2 to 63 percent of people on the drug
Increased sleepiness or dizziness may occur if you drink alcohol while taking topiramate
Mental problems Nephrolithiasis can occur with topiramate
Topamax is also used to prevent migraine headaches in adults and teenagers who are at least 12 years old
Weight Loss With Metformin & Topamax Together