Trazodone is an anti-anxiety medication often prescribed by vets to ease short-term anxiety in dogs and cats
At the ASPCA Animal Poison Control Center we become concerned with naïve dogs who are exposed to trazodone at 5 mg/kg, though mild signs can be seen at doses lower
Trazodone is an antidepressant that can lead to serious withdrawal symptoms and health problems if not taken properly
Trazodone selectively blocks serotonin reuptake, which enhances serotonin’s effects
Although not all of these side effects may occur, if they do occur they may need medical attention
Comments: Patients should be screened for a personal/family history of bipolar disorder, mania, or hypomania prior to initiating treatment
Trazodone may cause dry mouth
Symptoms will most often reach their peak within a week after they appear and then begin to decrease in their intensity
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It can be used to treat depression, anxiety disorders, and Trazodone withdrawal symptoms among other things
For the 36 dogs that completed the trial, the mean dog age was 3
Patients should be monitored for withdrawal symptoms when discontinuing treatment with trazodone hydrochloride tablets
Trazodone is rapidly absorbed in the gastrointestinal tract after oral administration, with a bioavailability ranging from 63-91% 9 and an AUC0−t of 18193
There do not seem to be any lasting harmful effects from taking it for many months, or even years
If your dose is 300mg a day or less, your doctor will probably tell you to take it as a single dose at bedtime
When using trazodone for sleep, the drug is given at low doses—typically between 25 to 100 milligram (mg)—which reduces the risk of drug tolerance and daytime sleepiness
It can also cause various side effects, such as drowsiness and headaches
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OBJECTIVE: While trazodone is approved for the treatment of depression, the off-label use of this medication for insomnia has surpassed its usage as an antidepressant
During the study, there were no adverse effects that required medical treatment, dosage adjustment, or withdrawal of trazodone
Typically, vets recommend that owners give dogs between 2
After a single dose in a healthy adult, trazodone will be mostly out of your system in one to three days